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Pharmacological properties

chinofucin suppositories have an antifungal effect on ascomycetes of the genus aspergillus and genus penicillium, yeast and yeast-like (candida albicans, etc.) fungi, as well as on dermatophytes. chinofucin suppositories have an antimicrobial effect with respect to gram-positive and gram-negative bacteria (streptococcus pyogenes, staphylococcus aureus, pseudomonas aeruginosa, proteus vulgaris, corinebacterium diphtheriae, salmonella spp., escherichia coli), and also amoeba albinalum (simplex).

The drug exhibits moderate hyperosmolar activity, as a result of which it absorbs vaginal discharge.

Pharmacokinetics Chlorchinaldol during vaginal administration is not absorbed and does not have a resorptive effect.

Indications

Treatment of colpitis and vulvovaginitis of fungal and non-specific bacterial etiology.

Application

Before applying the suppository, you must:

  • tear 1 suppository in the primary package along the perforation line of the blister pack;
  • then you need to pull the edges of the film, tearing it in different directions, and release the suppository from the primary packaging.

The drug is used in adult women vaginally, 1 suppository for 20 days or 1 suppository 2 times a day for 10 days. Before use, the suppository must be moistened with water. Therapy should be started at the beginning of the menstrual cycle.

Contraindications

Allergic reactions to chlorchinaldol.

Side effects

In some cases, in the presence of erosion, a burning sensation, allergic reactions (rash, itching in the genital area) may occur during the initial period of treatment.

special instructions

Due to the wide spectrum of antimicrobial action, it is used for mixed bacterial and fungal infections, especially at the beginning of treatment (until the identification of pathogens). it is advisable to avoid douching during the application of suppositories.

With vulvovaginal candidiasis, treatment must be carried out in combination with oral administration of nystatin tablets to eliminate foci of candidiasis infection in the gastrointestinal tract.

In case of nonspecific colpitis, combination therapy is recommended: intravaginal suppositories of Hinofucin, and oral administration of appropriate antibiotics of a systemic effect to inhibit infection in the urogenital tract. At the same time, the sexual partner should be treated.

Use during pregnancy and lactation. Given the possibility of developing general reactions, it is possible to use the drug during pregnancy and lactation only if the expected benefit from the use of the drug for the mother exceeds the possible risk to the fetus.

Children. It is not recommended to prescribe to children due to lack of clinical data.

The ability to influence the reaction rate when driving vehicles and working with other mechanisms. There is no data.

Interactions

No data on any interactions.

Overdose

In case of violation of the regimen and excess doses, allergic reactions may occur in the form of rashes and itching of the external genitalia. symptomatic therapy.

Storage conditions

At a temperature not exceeding 25 ° C.

Tags: Chinofucin [Chlorchinaldol]