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Pharmacological properties

The drug has a local effect on the mucous membrane of the nasal cavity, causing increased reflex secretion of the glands of the mucous membrane lining the paranasal sinuses and nasal cavity. enhanced reflex secretion in the form of serous-mucous secretions develops after a few minutes and lasts about 2 hours, contributing to the drainage of the paranasal sinuses and their release from the accumulated contents. the drug does not cause residual irritation of the mucous membrane, does not cumulate in the tissues of the nasal cavity and does not have a systemic effect.

Indications

  • Acute and chronic sinusitis - catarrhal or purulent sinusitis, frontal sinusitis, ethmoiditis, sphenoiditis or combined sinusitis; acute purulent sinusitis, accompanied by phenomena of a generalized infection or orbital complications (in the latter case, sinufort is used in combination with antibiotics); acute exudative inflammation of the middle ear (otitis media) and chronic exudative otitis media (in the latter case, treatment with sinuforte can be performed after myringotomy); acute and chronic rhinitis; acute allergic rhinitis or allergic rhinitis in the acute stage, including pollinosis as part of complex therapy, in order to prevent the development of purulent complications; postoperative rehabilitation after endoscopic surgical interventions (ethmoidotomy, maxillary ethmoidotomy, frontoetmoidogymorotomy).

Application

Each time you press the nebulizer-dispenser sprays 0.13 ml (2-3 drops) of the drug, which is a single dose (0.0013 g). the finished solution contains 35 doses of the drug. before use, open the cap of the bottle with the powder and remove the cork, open the ampoule with the solvent, breaking off the upper part; completely pour the solvent into the bottle with the drug, put the dispenser on the bottle and shake until completely dissolved, remove the protective cap and make 2-3 test sprays into the air, after which the bottle is ready for use.

The solution prepared by the above method is administered in the vertical position of the head by a single spray in each nasal passage.

For adults and children aged ≥5 years, the preparation prepared by the above method is administered with unilateral sinusitis on the side of sinusitis 1 time per day; with bilateral sinusitis, an aerosol is injected into each nasal passage. The drug is recommended to be used every other day, if necessary, its daily use is possible. The course of treatment is 12-16 days with the use of the drug every other day and 6-8 days with daily use.

To achieve a therapeutic effect, 6-8 injections of the drug are sufficient, however, a decrease in the severity of the headache or its complete disappearance can be noted after 3-5 injections of the drug. The dosage regimen and duration of use do not depend on the nosological form of the disease. After endoscopic surgery, intranasal administration of Sinuforte begins on the second day in order to drain the respiratory tract and reduce swelling of the mucous membranes.

Contraindications

Cystic-polypous sinusitis, the period of pregnancy and lactation, since the safety of use during these periods has not been studied; children aged 5 years, clinical data on the efficacy and safety of the drug in such children are insufficient; hypersensitivity to the components of the drug.

Side effects

Short-term sensation of mild or moderate burning sensation in the nasopharynx, reflex phenomena in the form of salivation, less often - short-term lacrimation and hyperemia of the skin of the face; in some cases, a short headache in the frontal region, discharge from the nose of a pale pink color as a result of capillary diapedesis. these phenomena do not require discontinuation of the drug.

special instructions

Avoid contact with eyes. do not inhale at the time of administration of the drug.

Unintentional contact with the drug in the eyes can cause severe irritation, as well as acute conjunctivitis.

In case of allergic rhinitis, the use of systemic antihistamines is permissible only 2 hours after the intranasal administration of Sinuforte. Antiallergic drugs can be used at least 8–10 hours before the intranasal administration of Sinuforte. When applying Sinuforte after surgery, there is no need to apply traditional postoperative rehabilitation measures, such as anemization, sinus flushing and toilet of the nasal cavity.

Increasing the dose of the drug does not increase the therapeutic effect.

Interactions

The simultaneous introduction into the nasal cavity of the drug Sinuforte and local anesthetics or antihistamines for topical use or the preliminary use of these drugs is unacceptable. if necessary, additional use of nasal dekongentantov (solutions containing epinephrine, ephedrine, etc.) is allowed. with purulent sinusitis, they are used simultaneously with antibiotics.

Overdose

Cases of overdose of sinuforte are not described. exceeding the recommended dose may be accompanied by a burning sensation and pain in the nasopharynx.

Storage conditions

In the dark place at a temperature of 15-25 ° C. freshly prepared solution is stored at a temperature of 8-10 ° C in a dark place for no more than 15 days.

Tags: Sinuforte