In stock
Guaranteed refund or reship if you haven't received your order
Secure and encrypted payment processing
We ship to over 40 countries including the USA, UK, Europe, Australia and Japan

Pharmacological properties

the active substance of the drug fencarol is a derivative of quinuclidylcarbinol, which reduces the effect of histamine on organs and systems. Quifenadine is a competitive blocker of H1 receptors. in addition, it activates the diamine oxidase enzyme, which breaks down about 30% of endogenous histamine. this explains the effectiveness of Quifenadine in patients insensitive to other antihistamines. Hiphenadine penetrates poorly through the BBB and has little effect on the processes of deamination of serotonin in the brain, weakly affects the activity of MAO. the antihistamine properties of Quifenadine are associated with the presence of a cyclic quinuclidine nucleus in the structure and the distance between the diphenylcarbinol group and the nitrogen atom. Quifenadine is superior to diphenhydramine in antihistamine activity and duration of action. reduces the toxic effect of histamine, in particular, eliminates or weakens its bronchoconstrictor effect and spasmodic effect on the smooth muscles of the intestine, has a moderate antiserotonin and weak cholinolytic effect, pronounced antipruritic and desensitizing properties. Quifenadine reduces the severity of the hypotensive effect of histamine and its effect on the permeability of capillaries, does not directly affect cardiac activity and hell, does not have a protective effect in aconitic arrhythmias.

Quifenadine does not have a depressing effect on the central nervous system, but with individual hypersensitivity, a weak sedative effect is possible. The drug has low lipophilicity, so its content in brain tissues is low (0.05%), which explains the absence of a depressing effect on the central nervous system.

Pharmacokinetics Hifenadine is rapidly absorbed in the digestive tract and after 30 minutes the drug is determined in the tissues of the body. Cmax in plasma it is achieved in 1 hour. Metabolites and an unchanged part of Quifenadine are mainly excreted in urine, bile and excreted by the lungs within 48 hours. Fencarol is metabolized in the liver.


Pollinosis, food and drug allergies, other allergic diseases, acute and chronic urticaria, angioedema (angioneurotic) Quincke, hay fever, allergic rhinopathy, dermatoses (eczema, psoriasis, neurodermatitis, skin itching), as well as infectious-allergic reactions with bronchospastic component.


Fencarol is taken orally immediately after a meal.

10 mg tablets Children aged 3–7 years - 10 mg 2 times a day (daily dose should not exceed 20 mg); children aged 7-12 years old - 10 mg 2-3 times a day (daily dose should not exceed 50 mg), children over 12 years old - 25 mg 2-3 times a day (daily dose should not exceed 100 mg).

For adults and children over the age of 12, it is advisable to use the drug in another dosage form (Fencarol, 25 mg tablets)

The duration of the course of treatment is 10-15 days. If necessary, repeat the treatment.

25 mg tablets A single dose for adults - 25-50 mg 2-4 times a day. With pollinosis, a daily dose of 75 mg is ineffective. The maximum daily dose is 200 mg. The duration of the course of treatment is 10-20 days.

Children over the age of 12 years - 25 mg 2-3 times a day. The duration of the course of treatment is 10-20 days.

If necessary, repeat the treatment.

50 mg tablets Adults - 50 mg 2-4 times a day. The maximum daily dose is 200 mg. The duration of treatment is 10–20 days. Repeat the treatment if necessary.

If the next dose has not been taken on time, you should continue the course of treatment using the previously prescribed doses. If necessary, consult a doctor.


Hypersensitivity to Quifenadine or excipients of the drug.

Side effects

From the nervous system: dizziness, headache.

Sometimes a slight sedative effect is possible, which manifests itself in the form of weakness, drowsiness, and a slowdown in the bodys response.

From the gastrointestinal tract: dryness of the mucous membranes of the oral cavity, dyspeptic symptoms (nausea, vomiting, bitterness in the mouth), which usually disappear with a dose reduction or drug withdrawal.

From the respiratory system, chest and mediastinal organs: sneezing, shortness of breath.

From the psyche: anxiety.

From the kidneys and urinary tract: proteinuria, interstitial nephritis.

From the side of musculoskeletal and connective tissue: joint pain.

From the side of the organ of vision: lacrimation.

In people with gastrointestinal diseases, the possibility of side effects increases.

If any side effects occur, discontinue use of the drug and consult a doctor.

special instructions

Caution should be exercised in severe diseases of the cardiovascular system, gastrointestinal tract or liver. the preparation contains sucrose, which should be considered for patients with diabetes mellitus. patients with rare hereditary diseases, such as fructose intolerance or sucrose-isomaltase deficiency, should not take the drug.

Use during pregnancy and lactation. It is contraindicated to prescribe the drug in the first trimester of pregnancy. Its use in the II and III trimester of pregnancy is not recommended. There is no data on the penetration of the drug into breast milk, so the use of the drug Fencarol during lactation is contraindicated.

Children. 10 mg tablets are used in children from 3 years of age, 25 mg tablets - from 12 years old, 50 mg tablets - there is no experience with children.

The ability to influence the reaction rate when driving vehicles or working with other mechanisms. Individuals whose work requires a quick physical or mental reaction (drivers of vehicles, etc.) should first establish individual sensitivity (by means of a short appointment) for sedation. These persons must be especially careful.


Fencarol does not enhance the inhibitory effect of alcohol and sleeping pills on the central nervous system. fencarol has weak m-anticholinergic properties, therefore, by reducing motility, the gastrointestinal tract is able to enhance the absorption of slowly absorbed drugs (for example, anticoagulants of the indirect action of the coumarin series).


A daily dose of up to 300 mg / day does not cause severe side effects. in a high dose, it can cause mucous membrane dryness, headache, epigastric pain, vomiting, and other dyspeptic symptoms. there is no specific antidote. if necessary, carry out symptomatic treatment.

Storage conditions

In a dry, dark place at a temperature of no higher than 25 ° c.