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Pharmacological properties

Trivalumen is a combined herbal preparation, the effect of which is due to the synergistic properties of its components. esters of borneol and isovaleric acid contained in valerian reduce central nervous system excitability, tension and irritability during psychic overload, exhibit sedative, hypnotic, antispasmodic properties, have choleretic effect, enhance secretory activity of the gastrointestinal glands, slow the heart rate, expand the coronary vessels of the heart . the activity of hop cones is caused by essential oil and a bitter resin containing bitter substances (humulon, lupulon and aliphatic turpentine alcohols), phytoncide substances, vitamins B and C, tocopherols and substances that have an estrogenic effect. they increase appetite, improve bile excretion, exhibit a diuretic effect, as well as a sedative effect in the state of arousal and insomnia, have an anti-inflammatory effect, and cause analgesic properties.

The pharmacological effect of peppermint is mainly associated with menthol, as well as terpenes, tannins, a bitter substance and organic acids. Peppermint components exhibit analgesic, astringent, anti-inflammatory effect; reduce the manifestations of nausea, gently stimulating the secretion of the glands of the gastrointestinal tract and liver, increase appetite, normalize intestinal motility.

The three-leaved shift due to bitter glycosidic compounds, flavonoids enhances gastrointestinal secretion, improves digestion, increases appetite, normalizes intestinal motility, and has antihypoxic and antioxidant effects.

The drug does not cause addiction, does not inhibit the psychomotor function, does not reduce performance.

Indications

Insomnia due to nervous and mental fatigue; neurocirculatory dystonia with tachycardia, cardialgia and ag; decreased appetite.

Application

Adults and children over the age of 12 years are prescribed 1 capsule 2-3 times a day; in the initial form of insomnia - 1 capsule 1–1.5 hours before bedtime. the duration of therapy is 7-15 days. the course of treatment can be repeated after 10 days.

Contraindications

  • Hypersensitivity to the drug, arterial hypotension, depression, drowsiness, gallstone disease, cholangitis, severe liver dysfunction; galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome; pregnancy and lactation; under 12 years old.

Side effects

CNS: headache, lethargy, drowsiness, depression, general weakness, decreased ability to work, concentration of attention; in some cases - mental agitation, anxiety, insomnia.

Cardiovascular system: arterial hypotension, pain behind the sternum, pain in the heart, heart rhythm disturbance (including bradycardia, tachycardia), hot flashes.

Gastrointestinal tract: heartburn, nausea, abdominal cramps, dyspeptic symptoms, inhibition of the digestive process, diarrhea.

Hepatobiliary system: possible manifestations of hepatotoxicity.

Allergic reactions: with individual hypersensitivity to the components of the drug, skin rash, itching, urticaria, hyperemia, edema, shortness of breath are possible.

Adverse reactions occur extremely rarely, are reversible, usually develop with the use of the drug for a long time and a significant excess of the recommended doses.

In the event of any adverse events, the patient must consult a doctor.

special instructions

Do not exceed recommended doses of the drug.

Since peppermint is part of the drug, patients with gastroesophageal reflux, achlorhydria, and hiatal hernia should avoid the use of the drug due to a possible increase in the severity of the symptoms of the disease. It is necessary to use the drug with caution in AD.

Valeryana, which is part of the drug, can exhibit a moderate depressive effect, so the combined use of Trivalemen with sleeping pills, other sedatives, and alcohol is not recommended due to the potentiation of the effect.

The composition of the tablets includes lactose, so the drug should not be used in patients with rare hereditary forms of galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome.

Use during pregnancy and lactation. The drug is contraindicated during pregnancy.

When using the drug in women breastfeeding, breastfeeding should be discontinued.

Children. In children under the age of 12 years, the drug is not used.

The ability to influence the reaction rate when driving vehicles or working with mechanisms. When using the drug, one should refrain from driving vehicles and working with potentially dangerous mechanisms.

Interactions

The drug can potentiate the effect of sleeping pills, antispasmodics, central antihypertensive drugs, tranquilizers, antipsychotics, alcohol, nootropic, analgesic drugs, drugs for anesthesia, curariform muscle relaxants. combined use with synthetic sedative drugs is not recommended.

Overdose

Symptoms: headache, drowsiness, weakness, lethargy, lethargy, dizziness, increased fatigue, depressed state, abdominal cramps, abdominal pain, nausea, mydriasis, decreased hearing and visual acuity, tremor of the extremities, compression sensation behind the sternum, tachycardia / bradycardia, decline in hell. when these reactions appear, stop taking the drug.

Treatment: symptomatic.

Storage conditions

In the original packaging at a temperature not exceeding 25 ° C.

Tags: Trivalumen