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Osteolon injection solution is used for degenerative joint changes: gonarthrosis, interdigital joint arthrosis, coxarthrosis, spondylosis, spondylarthrosis, meniscopathy, patella chondromalacia.


The active substance is an extract from bone marrow and intercostal cartilage of young calves (1 ml of solution contains 1 ml of extract from bone marrow and intercostal cartilage of young calves, containing at least 2.25 mg glycosaminoglycan-peptide complex).

Excipients: metacresol, 0.1 M hydrochloric acid, water for injection.


  • hypersensitivity to the components of the drug;
  • rheumatoid arthritis;
  • age up to 18 years;
  • During pregnancy and breastfeeding.

Mode of application

The drug is administered deeply intramuscularly: on the first day - 0.3 ml, on the second day - 0.5 ml and then 3 times a week, one ml for 5-6 weeks. A second course of treatment is carried out according to the same scheme, after consulting a doctor.

Application features


Osteolon is not recommended for use in children, since there is no data on the safety and effectiveness of treatment in this category of patients.


No cases of overdose were observed.

Side effects

Side effects by frequency of occurrence are classified into the following categories: very often (≥ 1/10), often (≥ 1/100 - <1/10), infrequently (≥ 1/1000 - <1/100), rarely (≥ 1 / 10000 - <1/1000), very rarely (<1/10000), unknown (frequency not determined by available data).

On the part of the immune system: rarely - allergic reactions, including anaphylactoid reactions, anaphylactic shock, edema of the neck.

From the musculoskeletal system: sometimes after 3-6 injections, there is an increase in joint pain, which goes away on its own and does not require drug withdrawal.

If there are side effects not described in this instruction, you should stop taking the drug and inform your doctor.

Storage conditions

Store in the original packaging at a temperature not exceeding 25 ° C, out of the reach of children.

Shelf life is 5 years.