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Composition:


active ingredients: levomentol, methyl salicylate;


1 g of ointment contains: levomentol 39 mg, methyl salicylate 202 mg;


excipients: soft yellow paraffin, paraffin.


Dosage form. Ointment.


Basic physical and chemical properties: ointment from white, yellowish-white to yellow color with the smell of menthol and methyl salicylate.


Pharmacotherapeutic group.


Topical remedies for joint and muscle pain. ATX code M02A C.


Pharmacological properties.


Pharmacodynamics. Combined preparation for external use.


Methyl salicylate has anti-inflammatory, analgesic, irritating and distracting effects, which are based on the effect on increased capillary permeability, microcirculation processes, inhibition of the activity of inflammatory mediators, including bradykinin, which has an algogenic effect. Menthol irritation of sensitive nerve endings leads to a slight local analgesic effect.


Pharmacokinetics. The drug is intended for topical use, so no absorption studies have been conducted.


Clinical characteristics.


Indications.


Rheumatism (joint and muscle), sciatica, arthritis, neuralgia, exudative pleurisy.


Contraindications.


Increased individual sensitivity to the components of the drug, skin diseases, injuries, skin wounds at the site of application of the drug. Hypersensitivity to acetylsalicylic acid, ibuprofen, or other nonsteroidal anti-inflammatory drugs, especially if you have a history of bronchial asthma.


Interactions with other drugs and other types of interactions. Although sufficiently controlled interaction studies have not been conducted, it is possible that excessive topical use of salicylates may increase the effect of coumarin anticoagulants and antiplatelet drugs. Caution should be exercised in patients taking coumarin anticoagulants and Antiplatelet medications, including aspirin.


Application features.


Prevent the ointment from getting into your eyes. In case of accidental contact with the ointment in the eyes, rinse them with water and immediately consult a doctor.


Do not use in persons prone to allergic reactions to the components of the drug.


Apply the product to undamaged areas of the skin.


Wash your hands thoroughly after each application of the ointment. In case of severe skin irritation, rubbing should be stopped.


Do not use with an occlusive dressing.


The drug contains salicylates, which are aspirin-like substances, so you should take into account warnings regarding the use of aspirin.


Use during pregnancy or lactation. The safety and efficacy of the drug during pregnancy and lactation have not been studied.


Ability to influence the reaction rate when driving vehicles or other mechanisms. It doesn't affect you.


Dosage and administration.


The drug is used externally. Rub 2-3 times a day into painful areas of the body, including the chest (with pleurisy). After rubbing the ointment, it is recommended to apply a dry warming bandage. The duration of use is determined by the nature and severity of the disease, the nature of concomitant therapy, and the effect achieved.


Children. Do not use in children under 3 years of age due to the menthol content in the preparation.


Overdose.


Increased manifestations of adverse reactions or a feeling of strong heat and burning at the site of application of the ointment.


Adverse reactions.


A feeling of cold, then heat, a slight burning and tingling sensation. Possible allergic reactions, including redness of the skin, rashes, urticaria, contact dermatitis, itching, which require discontinuation of the drug. Skin burns, blisters, and temporary skin reactions may occur.


Expiration date. 3 years.


Storage conditions. Store in the original packaging at a temperature not exceeding 25 °C.


Keep out of reach of children. chest (with pleurisy). After rubbing the ointment, it is recommended to apply a dry warming dressing.

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