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Affida Max tablets are indicated for the symptomatic treatment of headache and toothache, dysmenorrhea, neuralgia, back pain, joints, muscles, rheumatic pains, as well as signs of colds and flu.

Structure

Active ingredient: 1 tablet contains ibuprofen - 400 mg;

Excipients:

  • Kernel: corn starch, microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, talc, magnesium stearate.
  • Shell: sucrose; acacia; white suspension: sucrose, acacia, titanium dioxide (E 171), talc, magnesium stearate, calcium carbonate, castor oil, polyethoxylated, purified water.
  • Opalux AS 1198 Pink: sucrose, titanium dioxide (E 171), erythrosine (E 127), sodium benzoate (E 211), purified water.
  • Opaglos 6000 white: shellac, white wax, carnauba wax.

Contraindications

  • Hypersensitivity to ibuprofen or to any of the components of the drug.
  • Hypersensitivity reactions (e.g. bronchial asthma, rhinitis, angioedema or urticaria) after the use of acetylsalicylic acid (aspirin) or other non-steroidal anti-inflammatory drugs (NSAIDs).
  • Gastrointestinal bleeding or perforation associated with a history of NSAIDs.
  • Peptic ulcer of the stomach and / or duodenum in an active form or relapse in history (two or more pronounced episodes of peptic ulcer or bleeding).
  • Severe renal, cardiac, or liver failure.
  • The last trimester of pregnancy.
  • Cerebrovascular or other bleeding.
  • Violations of blood formation or blood coagulation.
  • Severe dehydration.

Mode of application

For use with short-term use.

The minimum effective dose should be used for the shortest possible period necessary to get rid of the symptoms. The patient should consult a doctor if it is necessary to use the drug for more than 10 days, if the symptoms do not disappear or worsen.

The drug is intended for adults and children over 12 years old. Apply 1 tablet every 4-6 hours. Drink the tablets with water.

Do not take more than 3 tablets in 24 hours.

The maximum daily dose is 1200 mg.

Elderly people do not need special dosing.

Patients with impaired renal and hepatic function of a mild or moderate degree do not require dose adjustment.

Application features

Pregnant women

Not recommended.

Children

Do not prescribe to children under the age of 12 years.

Drivers

Subject to the use of the recommended doses and duration of treatment, the drug does not affect the reaction rate when driving or working with other mechanisms. Patients experiencing dizziness, drowsiness, disorientation, or visual impairment when taking NSAIDs should abandon driving or working with machinery.

Overdose

The use of ibuprofen in children at doses greater than 400 mg / kg may cause symptoms of intoxication. In adults, the dose effect is less pronounced. The half-life with an overdose is 1.5-3 hours.

Side effects

The most common adverse reactions are from the gastrointestinal tract and are mainly dose-dependent.

  • From the digestive tract: abdominal pain, dyspepsia, nausea, diarrhea, flatulence, constipation, vomiting, peptic ulcer, perforation or gastrointestinal bleeding, melena, bloody vomiting, sometimes fatal (especially in elderly patients), ulcerative stomatitis , gastritis, pancreatitis, exacerbation of colitis and Crohns disease.
  • From the cardiovascular system: heart failure, edema.
  • From the nervous system: headache, aseptic meningitis, individual symptoms of which (stiff neck, headache, nausea, vomiting, fever and loss) can occur in patients with autoimmune diseases such as systemic lupus erythematosus, mixed connective tissue disease; paresthesia drowsiness.
  • On the part of the kidneys and urinary system: acute renal failure and papillary necrosis, especially with prolonged use, which is associated with an increase in the level of urea in blood plasma, edema, renal failure, nephrotoxicity, including interstitial nephritis and nephrotic syndrome.
  • On the part of the liver and biliary tract: impaired liver function, with prolonged treatment, hepatitis and jaundice may occur.
  • From the vascular system: arterial hypertension, arterial thrombosis (myocardial infarction or stroke).

Interaction

Ibuprofen, like other NSAIDs, should not be used in combination with:

  • acetylsalicylic acid (aspirin), as this can increase the risk of adverse reactions, except when the doctor has prescribed an aspirin (dose not higher than 75 mg per day);
  • other NSAIDs, including selective COX-2 inhibitors, as this can lead to an increase in the incidence of side effects.

Storage conditions

Keep out of reach of children at a temperature not exceeding 25 ° C.

Shelf life is 5 years.

Tags: Affida [Ibuprofen]