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Pharmacological properties

Citrulline malate is an equimolecular mixture of malate and l-citrulline. malate stimulates the krebs cycle and activates the mechanism of energy production at the cellular level, reduces the level of lactate in the blood and tissues, prevents the development of lactic acidosis and increases the level of atf. Citrulline is one of the amino acids that enters the urea cycle, activates the formation and excretion of urea from the body.

Citrulline malate is rapidly absorbed in the intestines. Cmax achieved after 45 minutes, exceeding the initial concentration by 6–15 times, and returns to the initial level after 5–6 hours.

Indications

Symptomatic treatment of functional asthenia:

  • physical fatigue;
  • mental asthenia;
  • postinfectious asthenia;
  • postoperative asthenia;
  • asthenia in old age;
  • asthenia in athletes;
  • hypovascular vegetative dystonia;
  • alcohol withdrawal syndrome;
  • sexual asthenia.

The drug is indicated for symptoms of asthenia: general weakness, emotional lability, chronic fatigue, low ability to work, drowsiness.

The drug is indicated for muscle pain and cramps that appear due to the accumulation of lactate after exercise. The drug is recommended during the period of convalescence of diseases that lead to the development of asthenovegetative syndrome.

Application

Applied inside, after dissolving the contents of the bag in 100 ml of water or a sweetened drink. take with meals.

Adults: 1 sachet 3 times a day.

Children over the age of 6 years: 1 sachet 2 times a day.

The recommended course of treatment is 4 weeks.

Contraindications

Hypersensitivity to any component of the drug. stomach ulcer or duodenal ulcer.

Side effects

In rare cases, slight pain in the epigastrium, allergic reactions are possible.

special instructions

1 sachet of stimol in the form of a solution contains about 30 mg (1.3 mmol) of sodium to bring ph solution to 3.3; in powder form, 100 mg of sodium. this must be taken into account when prescribing the drug to patients on a salt-free diet.

Since the powder contained in the bag is an acidic substance, it should be diluted in a glass of water or a sweetened drink and taken with meals.

Use during pregnancy and lactation. Do not use during pregnancy or lactation.

Children. The effectiveness and safety of the drug for children under 6 years of age are not well understood. The drug is used for children over the age of 6 years.

The ability to influence the reaction rate when driving vehicles or working with other mechanisms. Does not affect.

Interactions

Not found.

Overdose

Not described.

Storage conditions

Store at a temperature not exceeding 25 ° C out of the reach of children.

Tags: Stimol® [Citrulline Malate]