- Available:In stock1351
- Availability date:2020-07-30
- Dosage form:Cream
- In stock:1351 Items
topical preparation. the constituents of the cream have a combined effect in the treatment of inflammatory skin changes of an allergic etiology, additionally complicated by a bacterial infection, the course of which is accompanied by hyperkeratosis.
Betamethasone dipropionate is a synthetic fluoride derivative of hydrocortisone. It penetrates easily through the skin, providing a strong local anti-inflammatory, antipruritic and anti-allergic effect. Eliminates the causes of the formation of inflammatory processes, prevents the release of histamine and the appearance of local allergy symptoms. Due to the local vasoconstrictor effect, it reduces exudative reactions.
Gentamicin sulfate is a broad-spectrum antibiotic. It has an antibacterial effect against gram-negative and some gram-positive bacteria. Indications for its use in the form of an ointment are secondary infections in skin diseases if the infection is caused by bacteria that are sensitive to gentamicin, as well as if such an infection is suspected.
Pharmacokinetics Betamethasone dipropionate is not biotransformed in the skin (absorption does not exceed 1%). After penetration through the skin into the body, it is biotransformed in the liver and excreted mainly in the urine, in a smaller amount - with bile. The absorption of betamethasone dipropionate through the skin increases when applied to delicate skin, in the crease area, when applied to skin with damaged epidermis or skin damaged by an inflammatory process. In addition, absorption increases with frequent use of the drug or after application on a large surface of the skin. The absorption of betamethasone dipropionate through the skin in young people is more pronounced than in adults.
Gentamicin sulfate after topical application to intact skin is not absorbed, but after application to skin damaged by trauma, burns and ulcers, it may undergo systemic absorption.
Gentamicin sulfate is not biotransformed in the body and excreted unchanged in the urine.
Wet inflammatory skin conditions complicated by a secondary bacterial infection, accompanied by hyperkeratosis, itching, or severe allergic reactions, atypical dermatitis, seborrheic dermatitis, simple chronic lichen, psoriasis, allergic contact dermatitis.
Belogent cream, used only externally.
The cream is applied in a thin layer, rubbing slightly, on the affected surface of the skin 2-3 times a day, depending on the severity of the condition. Do not apply the cream under an occlusive dressing. If it is absolutely necessary to use a dressing, you must apply a dressing that allows air to pass through and do not use a sealing, oilcloth dressing. Do not treat for 2 weeks. Do not use for 1 week 45 g of cream!
Hypersensitivity to corticosteroids, gentamicin or the components of the drug. viral, fungal or tuberculous skin diseases, skin reactions after vaccination, skin neoplasms, rosacea, chicken pox, HIV infection, herpes zoster, open-angle glaucoma, phlebitis and trophic ulcers. During pregnancy and breastfeeding. Do not use on large areas of affected skin, especially in cases of impaired skin integrity, such as burns. do not apply on face skin. children under 2 years old.
When using the drug, especially under an occlusive dressing, you may experience a burning sensation, itching, irritation, dryness, folliculitis, acne, local hypo- or hyperpigmentation, perioral dermatitis, maceration of the skin, secondary infection, atrophy of the skin, striae, and sweating.
When used for longer than the recommended period, acne, steroid purpura, inhibition of epidermal growth, atrophy of the subcutaneous tissue, expansion of small blood vessels, and folliculitis can occur.
When applied to the skin of the face, oral dermatitis is possible.
After application on the skin, the eyelids can sometimes cause an increase in the manifestations of glaucoma or accelerate the development of cataracts.
With prolonged use, the drug can cause a significant general effect, characterized by the appearance of edema, hypertension, and a decrease in resistance to infection.
Belogent cream is used to treat wet, acute dermatosis.
If hypersensitivity reactions are observed when using the drug (skin irritation, accompanied by itching, burning and redness), therapy should be stopped immediately.
The use of Belogent cream for occlusive dressings is not recommended, except when necessary. The use of the drug on the skin of the face is not recommended due to the possible occurrence of dermatitis, such as rosacea, perioral dermatitis and acne.
Do not use on large areas of affected skin, especially in cases of impaired skin integrity, such as burns. Do not use in children under 2 years of age.
Belogent cream cannot be used to treat the eyes and around the eyes due to the possible development of cataracts, glaucoma, fungal diseases of the eyes, as well as exacerbation of herpes.
The drug is not used for treatment of varicose veins under the knees (leg ulcer).
After applying the cream to the skin, do not apply an oilcloth dressing, which leads to an increase in moisture and an increase in skin temperature.
Certain places on the body, such as the groin, armpits, perianal areas where there is natural occlusion, are sensitive to the appearance of stretch marks during treatment with the drug, so the use of the drug in these areas should be limited as much as possible.
With prolonged use of the cream on a large surface of the body, its absorption increases and the incidence of adverse reactions, such as edema, hypertension, increased blood glucose, and decreased body resistance, increase.
When there is an increase in the action of infection at the place of use, additional antimicrobial or antifungal treatment can be prescribed.
It should be remembered that long-term local therapy with gentamicin can cause the development of microorganisms resistant to aminoglycosides. Therefore, topical therapy is not recommended in immunocompromised patients or other high-risk patients. If during treatment there is resistance to the development of superinfection, treatment with gentamicin should be suspended and appropriate therapy prescribed.
The patient must inform the doctor about all adverse reactions that occurred during the use of the drug.
The ability to influence the reaction rate when driving a vehicle or working with machinery. There are no data on the effect of the drug Belogent cream on the ability to drive a vehicle or work with mechanisms.
Use during pregnancy and lactation. It is not recommended to use the drug during pregnancy and lactation.
If it is necessary to use Belogent cream, breast-feeding should be discontinued. Avoid contact of the child with the area of the skin of the mother on which the cream is applied.
Children. Do not use to treat children under 2 years of age.
Use in children is possible only as directed and under the supervision of a doctor.
Since the ratio of the surface of the skin of the body to body weight in children is higher than in adults, increased absorption with local application is possible, which can lead to systemic toxic effects. Therefore, it is necessary to use the drug in children with great care and in a minimally short period.
During treatment of corticosteroids, preventive vaccinations should not be carried out.
After prolonged use on a large surface of the skin, a decrease in the bodys resistance to infections, the manifestation of ag, edema is possible.
In the case of applying the drug to large affected areas of the skin for a long period (3 weeks) and with the use of an occlusive dressing, as well as with prolonged use in children with renal insufficiency, increased absorption and manifestation of a systemic effect may occur, while it is possible to develop inhibition of the hypothalamus system - pituitary gland - adrenal glands with growth retardation, hyperglycemia, glucosuria and Cushings syndrome.
Excessive or prolonged treatment with gentamicin can lead to exacerbation of fungal diseases or the development of superinfection.
Therapy for overdose. In case of an overdose, the drug must be discontinued. Therapy is symptomatic with the use of conventional measures to maintain the normal functioning of the body. If necessary, correct the electrolyte balance. In case of chronic toxic effects, gradual discontinuation of the drug is recommended.
Store at a temperature not exceeding 25 ° C.