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DISOL infusion solution

Instruction manual

On the medical use of the drug

Disol

(disolum)

Structure:

Active ingredients: sodium acetate trihydrate, sodium chloride;

100 ml of the solution contain: sodium acetate trihydrate - 200 mg, sodium chloride - 600 mg;

ionic composition per 1000 ml of the drug: Na+ - 117 mmol, Cl¯ 103 mmol; acetate 15 mmol;

excipient: water for injection.

Dosage form.

Solution for infusion.

Basic physical and chemical properties: transparent, colorless liquid; theoretical osmolarity - 235 mosmol / l, pH 6.5–7.5.

Pharmacotherapeutic group.

Solutions used to correct electrolyte imbalance. electrolytes.

Code ATX B05V B01.

Pharmacological properties.

Pharmacodynamics

Restores the volume of circulating blood. Reduces hyperkalemia and its consequences in the treatment of water-salt disorders, improves capillary circulation and kidney function. Detects a detoxification effect due to a short-term increase in fluid volume, a decrease in the concentration of toxic products in the blood, and activation of diuresis.

Pharmacokinetics

The drug is not in the vascular bed for a short time, quickly passes into the interstitial space and is metabolized in the liver. It is excreted by the kidneys, enhancing diuresis.

Clinical characteristics.

Indications.

Correction of hyperkalemia and its consequences during dehydration and intoxication of the body that occur with various infectious diseases (acute dysentery, foodborne toxicosis, cholera el tor).

Contraindications

Hypersensitivity to the components of the drug. the threat of developing cerebral and pulmonary edema, hyperhydration.

Interaction with other drugs and other types of interactions.

Not installed.

Features of the application.

Before use, the solution is heated to + 36–38 wasps. use with caution in patients with impaired renal excretory function, with decompensated heart defects, with edematous ascites syndrome in patients with cirrhosis of the liver.

Use during pregnancy or lactation.

There is no experience with the use of the drug during pregnancy or lactation.

The ability to influence the reaction rate when driving vehicles or other mechanisms.

Data on the effect of the drug on the reaction rate when driving or working with other mechanisms are not available, since the drug should be used exclusively in a hospital.

Dosage and administration.

Introduce intravenously. before use, warm the solution to + 36–38 wasps. the total amount of injected solution should correspond to the volume of fluid lost. balance the injected and lost fluid every 6 hours! after the elimination of hyperkalemia, further water-salt therapy should be carried out with Trisol, Acesol.

Children.

There are no data on the limitations of the use of the drug for children. adjust the dosage regimen depending on laboratory parameters. the total daily dose depends on the water-electrolyte balance and laboratory parameters.

Overdose.

Hypokalemia, hypernatremia. due to hyperhydration and hypervolemia, heart failure may develop.

Adverse Reactions

With individual intolerance to any component of the drug, hypersensitivity reactions are possible.

Shelf life.

5 years.

Storage conditions.

Store at a temperature not exceeding 25 ° C out of the reach of children.

Freezing the drug while maintaining the tightness of the bottle is not a contraindication to use. Non-wetting of the inner surface of the bottle is not a contraindication to the use of the drug.

Incompatibility.

There is no data on the incompatibility of disol with other drugs.

Packaging.

400 ml in bottles.

Vacation category.

On prescription.

Manufacturer.

Private joint-stock company "infusion".

The location of the manufacturer and his address of the place of business.

Ukraine, 21034, Vinnitsa, st. Voloshkova, 55 or Ukraine, 23219, Vinnitsa region, Vinnitsa district, s. Vinnytsia farms, st. Nemirovskoe highway, 84a.

Applicant

Private joint-stock company "infusion".

Location of the applicant and / or representative of the applicant.

Ukraine, 04073, Kiev, Moscow Avenue, d. 21-a.

Tags: Sodium Acetate Trihydrate, Sodium Chloride